Thermo Fisher Scientific GSC2 Polyclonal Antibody
Thermo Fisher Scientific의 GSC2 폴리클로날 항체는 인간 GSCL 단백질의 C-말단 펩타이드에 특이적입니다. WB 및 IHC에 적합하며, Protein A로 정제된 액상 형태입니다. 1 mg/mL 농도, PBS+2% sucrose buffer에 0.09% sodium azide 포함. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1.25 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human GSCL (aa 141–190) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2610338 |
Product Specific Information
Peptide sequence:
LEALFVQNQY PDVSTRERLA GRIRLREERV EVWFKNRRAK WRHQKRASAS
Sequence homology:
Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 85%; Human: 100%; Mouse: 100%; Rabbit: 85%; Rat: 100%; Zebrafish: 91%
Target Information
Goosecoidlike (GSCL) resides in the critical region for VCFS/DGS on 22q11.
Velocardiofacial syndrome (VCFS) is phenotypically related to DiGeorge syndrome (DGS), both associated with hemizygous 22q11 deletions.
Because many affected tissues in VCFS/DGS derive from the pharyngeal arches of the developing embryo, haploinsufficiency of a gene involved in embryonic development is believed to contribute to its etiology.
GSCL, a homeodomain-containing gene, is expressed in a limited number of adult tissues and during early human development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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