Thermo Fisher Scientific IQCG Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human IQCG. Recombinant protein control fragment (Product #RP-108206). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IQCG,uniProtId:Q9H095-1,ncbiNodeId:9606,antigenRange:106-198,antigenLength:443,antigenImageFileName:PA5-84096_IQCG_Q9H095-1_Rabbit.svg,antigenImageFileNamePDP:PA5-84096_IQCG_Q9H095-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2791248

Product Specific Information

Immunogen sequence: LDKLPMASTI TKIPSPLITE EGPNLPEIRH RGRFAVEFNK MQDLVFKKPT RQTIMTTETL KKIQIDRQFF SDVIADTIKE LQDSATYNSL LQA

Target Information

IQCG is a protein coding gene. Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin-dependent protein kinase IV (CAMK4) activity; contributes to the regulation of CAMK4 signaling cascades. Required for normal axoneme assembly in sperm flagella, normal sperm tail formation and for male fertility.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.