Thermo Fisher Scientific PUF60 Polyclonal Antibody
Human PUF60 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 적용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PUF60. Recombinant protein control fragment (Product #RP-104013) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791252 |
Product Specific Information
Immunogen sequence:
AATAKITAQE AVAGAAVLGT LGTPGLVSPA LTLAQPLGTL PQAVMAAQAP GVITGVTPAR PPIPVTIPSV GVVNPILASP PTL
Target Information
PUF60 encodes a Ro RNP-binding protein that interacts with Ro RNPs, potentially conferring a gain of function. It forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein, repressing a c-myc reporter via FUSE. It also targets transcription factor IIH and inhibits activated transcription. This gene is implicated in xeroderma pigmentosum disorder. Two alternatively spliced transcript variants encode different isoforms, and multiple polyadenylation sites are suggested.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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