Thermo Fisher Scientific EDG8 Polyclonal Antibody
Rabbit polyclonal antibody detecting human EDG8. Validated for IHC (Paraffin) with 4–7 µg/mL dilution. Targets the 2nd cytoplasmic domain of EDG8. Suitable for research use only, not for diagnostic purposes.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 4–7 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from 2nd cytoplasmic domain of human EDG8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2301274 |
Product Specific Information
PA1-33163 detects EDG8 from human samples.
Target Information
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand.
S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1) are S1P receptors; others (e.g., EDG2) are LPA receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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