Thermo Fisher Scientific ADAMTS4 Polyclonal Antibody
ADAMTS4 단백질을 검출하기 위한 Thermo Fisher Scientific의 토끼 폴리클로날 항체. 인간 시료 반응성 확인. IHC(P), IHC(F), ICC/IF 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제된 고품질 액상 항체로 연구용에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2 µg/mL
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: Not determined
- Publication: Available (1)
Immunocytochemistry (ICC/IF)
- Tested Dilution: Not determined
- Publication: Available (1)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from Disintegrin-like domain of human ADAMTS4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2222312 |
Product Specific Information
PA1-33177 detects ADAMTS4 from human samples.
Target Information
This gene encodes a member of the ADAMTS protein family. Members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 motif.
Individual members differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.
The enzyme encoded by this gene lacks a C-terminal TS motif and is responsible for the degradation of aggrecan (a major proteoglycan of cartilage) and brevican (a brain-specific extracellular matrix protein).
This cleavage suggests key roles of ADAMTS4 in arthritic disease and in the central nervous system, potentially in the progression of glioma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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