Thermo Fisher Scientific CaV3.1 Polyclonal Antibody
CaV3.1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 시료에 반응합니다. 항원 친화 크로마토그래피로 정제되었으며, IHC(P)에서 1:15–1:50 희석으로 사용 가능합니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
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Thermo Fisher Scientific CaV3.1 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:15–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the C-terminal of human calcium channel, voltage-dependent, T type, alpha 1G subunit (CaV3.1, UniProt ID: O43497-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.9 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636088 |
Product Specific Information
This antibody detects endogenous levels of total CACNA1G protein.
Target Information
Voltage-dependent Ca²⁺ channels mediate Ca²⁺ entry into excitable cells in response to membrane depolarization and are involved in various Ca²⁺-dependent processes such as muscle contraction, hormone or neurotransmitter release, and gene expression.
Calcium channels are multimeric complexes composed of:
- Alpha-1 subunit
- Intracellular beta subunit
- Disulfide-linked alpha-2/delta subunit
- Transmembrane gamma subunit
Ca²⁺ currents are classified by biophysical and pharmacologic properties into L-, N-, T-, P-, Q-, and R-types.
T-type Ca²⁺ currents are activated and inactivated more rapidly and at more negative membrane potentials than other types, enhancing odor sensitivity by lowering the threshold of spike generation in olfactory receptor cells (ORCs).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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