Thermo Fisher Scientific Melanophilin VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1233)
Recombinant alpaca VHH antibody targeting human Melanophilin (MLPH). Validated for ICC/IF applications. Produced in CHO cells and purified via metal-chelate chromatography. Supplied as liquid form, 1 mg/mL in PBS without preservative. For resea...
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Thermo Fisher Scientific Melanophilin VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1233)
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: Assay-dependent
Publications: Not specified
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1233 |
| Immunogen | Recombinant Human MLPH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Target Information
Slac2-a (synaptotagmin-like protein homolog lacking C2 domains-a) links Rab27A on melanosomes with Myosin VA in melanocytes.
It binds Myosin VA through a C-terminal region and GTP-bound Rab27A through its synaptotagmin-like protein homology domain (SHD) near the N-terminus.
Stable formation of this complex is required for pigment and cytotoxic granule transport in melanocytes.
Mutations in binding domains of these proteins may lead to albinism and/or immune disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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