Thermo Fisher Scientific PDE2A Polyclonal Antibody, FITC
FITC 결합된 PDE2A 폴리클로날 항체로, 인간·마우스·랫트에서 반응하며 WB, IHC, ICC 등 다양한 실험에 사용 가능. 합성 펩타이드 기반 면역원으로 제작, 고순도 친화성 정제. 액상 형태로 -20°C, 암소 보관.
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Thermo Fisher Scientific PDE2A Polyclonal Antibody, FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
| Fluorescence Resonance Energy Transfer (FRET) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to unique N-terminal amino acid sequence on PDE2A gene |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
PDE2A (phosphodiesterase 2A) is a 100 kD cyclic nucleotide phosphodiesterase (PDE). Three isoforms (PDE2A1, PDE2A2, PDE2A3) arise from a single gene by alternative splicing. PDE2A degrades both cAMP and cGMP, with higher efficacy for cGMP. It is expressed in various tissues, predominantly in the brain (cerebellum and neocortex). PDE2A is implicated in penile erectile dysfunction and regulation of fluid and inflammatory cell transport across the endothelial barrier.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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