Thermo Fisher Scientific Oncostatin M Polyclonal Antibody
Human Oncostatin M을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50–1:300 희석으로 사용 가능. Affinity chromatography로 정제된 액상 시약이며, PBS/glycerol buffer에 보관. 세포 증식 및 분화 관련 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:300
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human Oncostatin M [aa 50–100] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2688421 |
Product Specific Information
Predicted to react with Human samples.
Target Information
Oncostatin M (OSM) is a growth and differentiation factor involved in the regulation of neurogenesis, osteogenesis, and hematopoiesis. It is produced by activated T cells, monocytes, and Kaposi’s sarcoma cells, and can exert both stimulatory and inhibitory effects on cell proliferation. OSM stimulates proliferation of fibroblasts, smooth muscle cells, and Kaposi’s sarcoma cells, while inhibiting growth of certain normal and tumor cell lines. It also promotes cytokine release (e.g., IL-6, GM-CSF, G-CSF) from endothelial cells and enhances expression of low-density lipoprotein receptors in hepatoma cells. OSM shares structural and functional characteristics with LIF, IL-6, and CNTF.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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