Thermo Fisher Scientific CDY2B Monoclonal Antibody (OTI1A10), TrueMAB

Applications

• Western Blot (WB): 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

CDY2B encodes a protein containing both a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can function as gene repressors.
This protein localizes to the nucleus of late spermatids where histone hyperacetylation occurs, facilitating the transition in which protamines replace histones as the major DNA-packaging proteins.
Two nearly identical copies of this gene are found in a palindromic region on chromosome Y; this record represents the centromeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.