Thermo Fisher Scientific GRM2 Monoclonal Antibody (3H7)
GRM2 단백질을 인식하는 마우스 단클론 항체(3H7)로, ELISA에 적합합니다. 인간 시료에 반응하며 비결합형 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, PBS(pH 7.4) 버퍼에 보존제 없이 저장됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3H7 |
| Immunogen | GRM2 (NP_000830, 414–506 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
NGRRLYKDFV LNVKFDAPFR PADTHNEVRF DRFGDGIGRY NIFTYLRAGS GRYRYQKVGY WAEGLTLDTS LIPWASPSAG PLAASRCSEP CLQ
Target Information
Glutamate is the main excitatory neurotransmitter in the brain. It acts on ligand-gated receptor channels such as NMDA, AMPA, and kainate receptors, which are involved in fast excitatory synaptic transmission.
Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins, known as metabotropic glutamate receptors (mGluRs).
- Group I receptors (mGluR1a, mGluR5): Stimulate phospholipase C, increasing phosphoinositide turnover and calcium release.
- Group II and III receptors (mGluR2, mGluR3): Inhibit adenylyl cyclase.
Usage
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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