Thermo Fisher Scientific Caspase 4 Monoclonal Antibody (OTI4A2)
Human Caspase 4 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 고순도 Affinity Chromatography 정제, 액상 형태, 안정적 저장용 PBS 버퍼 포함.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:250
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4A2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 81–270 of CASP4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724038 |
Target Information
This gene encodes a protein that belongs to the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a key role in the execution phase of cell apoptosis. Caspases are synthesized as inactive proenzymes composed of a prodomain and large and small protease subunits. Activation requires proteolytic processing at conserved internal aspartic residues to form a heterodimeric enzyme. Caspase 4 can cleave and activate its own precursor as well as the caspase 1 precursor. Overexpression of this gene induces apoptosis. Alternative splicing results in distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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