Thermo Fisher Scientific CDH17 Polyclonal Antibody
Rabbit polyclonal antibody specific for human CDH17/Cadherin-17. Suitable for WB, IHC, ICC, ELISA, and IP. Preservative-free formulation; sodium azide addition recommended. Ideal for research on gastrointestinal and pancreatic tissue expression.
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Thermo Fisher Scientific CDH17 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:2,000–1:10,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ELISA | 1:25,000–1:50,000 |
| Immunoprecipitation (IP) | 1–2 µL/mg of lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CDH17/Cadherin-17 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Lot-specific |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long-term storage, store at -20°C. |
| Shipping Conditions | Wet ice |
| RRID | AB_2787772 |
Product Specific Information
- This product is preservative-free.
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
- This antibody has specificity for Human CDH17/Cadherin-17.
Target Information
The CDH17 gene belongs to the cadherin superfamily, encoding calcium-dependent, membrane-associated glycoproteins. The protein is cadherin-like, containing seven cadherin domains and a transmembrane region but lacking the conserved cytoplasmic domain.
CDH17 is expressed in the gastrointestinal tract and pancreatic ducts, functioning as an intestinal proton-dependent peptide transporter involved in the absorption of peptide-based drugs. It may also contribute to the morphological organization of liver and intestine.
Alternative splicing results in multiple transcript variants.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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