Thermo Fisher Scientific CEP290 Polyclonal Antibody
CEP290 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, ICC/IF, IP에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태입니다. 인간 시료 반응성이 있으며, 4°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunocytochemistry (ICC/IF) | 1:250–1:1,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 2429 and 2479 of human centrosomal protein 290 kDa |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4 °C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For ICC, formaldehyde fixation is recommended. Permeabilization with Triton‑X 100 is recommended for formaldehyde‑fixed cells.
Target Information
This gene encodes a protein with 13 putative coiled‑coil domains, a region homologous to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains, and an ATP/GTP binding site motif A.
The protein localizes to the centrosome and cilia and contains sites for N‑glycosylation, tyrosine sulfation, phosphorylation, N‑myristoylation, and amidation.
Mutations in this gene are associated with Joubert syndrome and nephronophthisis, and antibodies against this protein have been linked to several forms of cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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