Thermo Fisher Scientific FPR3, Formylpeptide Receptor 3 Polyclonal Antibody
Human FPR3 단백질에 특이적인 Rabbit Polyclonal Antibody로, Western Blot에 적합하며 항원 친화 크로마토그래피로 정제됨. 액상 형태로 1 mg/mL 농도이며, 단기 4°C 보관 및 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
- 카탈로그번호
- 7TM0224N
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific FPR3, Formylpeptide Receptor 3 Polyclonal Antibody
Thermo Fisher Scientific FPR3, Formylpeptide Receptor 3 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide representing part of the carboxyl-terminal tail of human FPR3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The N-formyl peptide receptor (FPR) family consists of three members: FPR, FPR3 (also known as FPRL1, lipoxin A4 receptor, FPRH1, or FPR2), and FPR-like 2 (FPRL2). These are chemotactic G protein-coupled receptors with seven transmembrane domains, found on phagocytic leukocytes such as neutrophils and monocytes.
FPR3 binds multiple ligands, including lipoxin A4, N-formyl-methionyl-leucyl-phenylalanine (fMLP), serum amyloid A (SAA), prion peptide, and the 42 amino acid form of beta amyloid. Activation of FPR3 induces migration and calcium mobilization in human monocytes and neutrophils, playing a role in inflammation and host defense.
FPR3 may mediate inflammatory processes in prion and Alzheimer’s diseases, making it a potential therapeutic target.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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