Thermo Fisher Scientific PKM Monoclonal Antibody (6C3C7)
PKM 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot, IHC, ICC, Flow cytometry, IP 등 다양한 응용에 적합합니다. Human, Mouse, Rabbit, Rat에 반응하며, 고순도 Protein G 정제 및 안정적인 보관이 가능합니다.
- 카탈로그번호
- MA538278
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PKM Monoclonal Antibody (6C3C7)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000–1:256,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 1:150–1:300 |
| Flow Cytometry (Flow) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1–4 µL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rabbit, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6C3C7 |
| Immunogen | Recombinant Human Pyruvate kinase PKM protein (2–531aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 4.66 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | –20°C or –80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898193 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein interacts with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. It also binds Opa protein, a bacterial outer membrane protein involved in gonococcal adherence and invasion of human cells, suggesting a role in bacterial pathogenesis. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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