Thermo Fisher Scientific OCT4 Polyclonal Antibody
OCT4 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간, 마우스, 랫트 시료에 반응. WB, IHC, ICC, ELISA 등 다양한 실험에 사용 가능. 고순도 Protein A 정제 및 안정적인 액상 형태로 제공. 줄기세포 연구 및 iPS 세포 생성 관련 연구에 적합.
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Thermo Fisher Scientific OCT4 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from mouse OCT-4 (amino acids 201–300) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
POU5F1, commonly known as Oct-4, is a maternally expressed octamer-binding transcription factor essential for early embryonic development. It plays a key role in maintaining pluripotency and self-renewal of stem cells. Expression of POU5F1, along with Sox2, Klf4, Lin28, and c-Myc, enables the generation of induced pluripotent stem (iPS) cells from somatic cells. Recent research shows that iPS cells can be produced using non-viral plasmid expression systems, offering safer approaches for regenerative medicine applications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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