Thermo Fisher Scientific PCDH1 Polyclonal Antibody
PCDH1 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 생쥐, 랫트 반응성. IHC, ICC/IF, ELISA 등 다양한 응용에 적합. Protein A로 정제된 고순도 액상 항체로 연구용으로 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human PCDH1, amino acids 51–150 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Protocadherin 1 (PCDH1), also known as cadherin-like protein 1, is a transmembrane protein involved in cell-cell adhesion. It belongs to the delta1-protocadherin family, which includes protocadherin-1, -7, -9, and -11(X/Y). These proteins have seven extracellular cadherin repeats, a transmembrane domain, and a cytoplasmic domain, and can be expressed in short or long isoforms.
PCDH1 expression is temporally and spatially regulated and plays roles in both early development and mature tissues. In mice, it is expressed in the brain, spinal cord, peripheral ganglia, inner ear, hair follicles, kidney, reproductive organs, prostate, and seminal gland.
PCDH1 is identified as a susceptibility gene for Bronchial Hyperresponsiveness in humans and is also expressed on human pluripotent stem cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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