Thermo Fisher Scientific PDE1B Monoclonal Antibody (OTI6E4), TrueMAB
PDE1B 단백질을 인식하는 마우스 모노클로날 항체로, WB, IHC, ICC/IF, Flow Cytometry에 적합합니다. 인간 유래 단백질을 면역원으로 제작되었으며, 비결합형 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific PDE1B Monoclonal Antibody (OTI6E4), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6E4 |
| Immunogen | Full-length human recombinant PDE1B protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The PDE1B gene encodes a member of the cyclic nucleotide phosphodiesterase (PDE) family, specifically the PDE1 subfamily. These enzymes are calmodulin-dependent and activated by calcium-calmodulin complexes. PDE1B shows dual specificity for cAMP and cGMP, with a preference for cGMP, both of which regulate key physiological processes. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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