Thermo Fisher Scientific TTF-1/NKX2.1 (Thyroid and Lung Epithelial Marker) Monoclonal Antibody (TTF1/8430)
TTF-1/NKX2.1 단백질을 인식하는 mouse monoclonal antibody로, 갑상선 및 폐 상피 세포 마커 연구에 적합. IHC(P), IHC(PFA) 등 다양한 면역조직화학 실험에 사용 가능. 고순도 Protein A/G 정제 및 안정한 PBS buffer 형태로 제공. 연구용 전용 시약.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TTF1/8430 |
| Immunogen | Recombinant human TTF-1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes, but has also been shown to regulate genes involved in morphogenesis.
Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may also be linked to thyroid cancer.
Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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