Thermo Fisher Scientific COX15 Polyclonal Antibody
COX15 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western Blot에 적합합니다. 인간에 반응하며, Mouse·Rat·Chicken·Bovine에서도 높은 예측 반응성을 보입니다. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공합니다.
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Applications
Tested Application
- Western Blot (WB)
Tested Dilution
- 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–254 of COX15 (Uniprot ID: Q7KZN9) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.52 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2552033 |
Product Specific Information
- Recommended positive controls: A431
- Predicted reactivity: Mouse (93%), Rat (92%), Chicken (92%), Bovine (94%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The cytochrome c oxidase (COX) family of proteins functions as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water.
The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some mitochondrial and some nuclear.
COX15 (cytochrome c oxidase assembly protein COX15 homolog) is a 410 amino acid multi-pass mitochondrial membrane protein belonging to the COX15/ctaA family.
Existing as two alternatively spliced isoforms, COX15 is predominantly expressed in tissues with high oxidative phosphorylation rates, including brain, heart, and muscle.
Defects in COX15 are associated with Leigh syndrome and cytochrome c oxidase deficiency (COX deficiency).
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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