Thermo Fisher Scientific H3K4acT3ph Polyclonal Antibody

Thermo Fisher Scientific H3K4acT3ph Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Store vial at -20°C prior to opening.
• Aliquot contents and freeze at -20°C or below for extended storage.
• Avoid cycles of freezing and thawing.
• Centrifuge product if not completely clear after standing at room temperature.
• Stable for several weeks at 4°C as an undiluted liquid.
• Dilute only prior to immediate use.

This antibody reacts with human Histone H3.
BLAST analysis suggests cross-reactivity with Human, Mouse, and C. elegans.
Predicted to react with Rat, Chicken, Xenopus, Drosophila, and Plant based on 100% sequence homology.
Cross-reactivity with Histone H3 from other sources has not been determined.

Target Information

Histones are basic nuclear proteins responsible for the nucleosome structure of the chromosomal fiber in eukaryotes.
Approximately 146 bp of DNA wraps around a nucleosome composed of pairs of the four core histones (H2A, H2B, H3, and H4).
The chromatin fiber is further compacted through interaction of linker histone H1 with DNA between nucleosomes, forming higher-order chromatin structures.
This gene is intronless and encodes a member of the histone H3 family. Transcripts lack polyA tails and contain a palindromic termination element.
Located within a histone cluster on chromosome 1, this gene is one of four duplicated histone genes; this record represents the telomeric copy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

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