Thermo Fisher Scientific SELS Polyclonal Antibody
Human SELS 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific SELS Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SELS. Recombinant protein control fragment (Product #RP-90222). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647100 |
Product Specific Information
Immunogen sequence:
EPDVVVKRQE ALAAARLKMQ EELNAQVEKH KEKLKQLEEE KRRQKIEMWD SMQEGKSYKG NAKKPQEEDS PGPSTSSVLK RKSDRKPLRG GGYNPLSGEG GGACSWRPGR
Highest antigen sequence identity to the following orthologs:
- Mouse: 86%
- Rat: 86%
Target Information
This gene encodes a transmembrane protein localized in the endoplasmic reticulum (ER). It is involved in the degradation of misfolded proteins in the ER and may play a role in inflammation control. The protein facilitates the transfer of misfolded proteins from the ER to the cytosol, where they are degraded by the proteasome in a ubiquitin-dependent manner.
This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec), encoded by the UGA codon. The 3′ UTRs of selenoprotein mRNAs contain a conserved stem-loop structure called the SECIS element, necessary for recognizing UGA as a Sec codon rather than a stop signal.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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