Thermo Fisher Scientific ALDH1A2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

5µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ALDH1A2. Recombinant protein control fragment (Product #RP-89838). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ALDH1A2,uniProtId:O94788-1,ncbiNodeId:9606,antigenRange:348-469,antigenLength:518,antigenImageFileName:PA5-52684_ALDH1A2_O94788-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52684_ALDH1A2_O94788-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637838

Product Specific Information

Immunogen sequence: VVGSPFDPTT EQGPQIDKKQ YNKILELIQS GVAEGAKLEC GGKGLGRKGF FIEPTVFSNV TDDMRIAKEE IFGPVQEILR FKTMDEVIER ANNSDFGLVA AVFTNDINKA LTVSSAMQAG TV

Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

Target Information

This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Three transcript variants encoding distinct isoforms have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.