Thermo Fisher Scientific SGK1 Polyclonal Antibody
SGK1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot에 최적화되어 있으며, 인간 및 생쥐에서 반응합니다. 항원 친화 크로마토그래피로 정제되었고, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific SGK1 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human SGK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.38 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792380 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (88%), Xenopus laevis (91%), Pig (95%), Rabbit (95%), Chicken (94%), Chimpanzee (100%), Bovine (95%).
- Positive Control: mouse brain.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
SGK (SGK1) is a serine/threonine kinase that may be a transcriptional target for p38/MAPK in hepatoma cells. SGK plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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