ELK Biotechnology UB2D3 rabbit pAb
UB2D3 단백질을 인식하는 토끼 폴리클로날 항체. WB 및 ELISA에 적합하며, 인간, 마우스, 랫트 시료에 반응. 세포막 및 엔도솜 막에 위치한 단백질 검출용. -20°C에서 1년 보관 가능.
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- pk
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UB2D3 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | UB2D3 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 16 kD |
| GeneID (Human) | 7323 |
| Human Swiss-Prot No | P61077 |
| Cellular Localization | Cell membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. |
| Species Reactivity | Human; Mouse; Rat |
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s).
This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.
[Provided by RefSeq, Jul 2008]
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