ELK Biotechnology VPP2 rabbit pAb
VPP2 rabbit polyclonal antibody for WB and ELISA applications. Recognizes human, rat, and mouse VPP2 protein. Targets vacuolar ATPase subunit involved in cellular acidification. Stable at -20°C for up to one year.
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ELK Biotechnology VPP2 rabbit pAb
제품 개요
VPP2 rabbit polyclonal antibody는 인간, 랫트, 마우스의 VPP2 단백질을 인식하며, WB 및 ELISA 분석에 적합합니다. 이 항체는 세포막 및 엔도좀 막에 위치하는 vacuolar ATPase 복합체의 V(0) 도메인 구성 요소를 표적합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | VPP2 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB: 1:500–2000, ELISA: 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 94 kD |
| GeneID (Human) | 23545 |
| Human Swiss-Prot No | Q9Y487 |
| Cellular localization | Cell membrane; Multi-pass membrane protein; Endosome membrane; In kidney proximal tubules, also detected in subapical vesicles |
| Species Reactivity | Human; Rat; Mouse |
Background
The protein encoded by this gene is a subunit of the vacuolar ATPase (v-ATPase), a heteromultimeric enzyme essential for acidification of intracellular compartments. V-ATPase consists of a peripheral V(1) domain for ATP hydrolysis and an integral membrane V(0) domain for proton translocation. The subunit encoded by this gene is part of the V(0) domain. Mutations in this gene are associated with cutis laxa type II and wrinkly skin syndrome. (RefSeq, Jul 2009)
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