ELK Biotechnology SYN3 rabbit pAb
SYN3 rabbit polyclonal antibody는 인간, 랫, 마우스에서 반응하며 WB와 ELISA에 적합합니다. 인간 SYN3 단백질 유래 합성 펩타이드로 면역화되었으며, 시냅스 소포의 세포질막 단백질 검출에 활용됩니다. -20°C에서 1년 보관 가능합니다.
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ELK Biotechnology SYN3 rabbit pAb
제품 개요
SYN3 rabbit polyclonal antibody는 인간 단백질에서 유래한 합성 펩타이드(AA 530–580)를 면역원으로 제작된 항체입니다. 시냅스 소포막의 세포질 표면에 위치한 SYN3 단백질을 검출하는 데 사용됩니다.
제품 스펙
| 항목 | 내용 |
|---|---|
| Product name | SYN3 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein (AA range 530–580) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 63 kD |
| GeneID (Human) | 8224 |
| Human Swiss-Prot No | O14994 |
| Cellular Localization | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein localized to the cytoplasmic surface of synaptic vesicles |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains and are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene’s localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction.
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