ELK Biotechnology TM2D1 rabbit pAb
TM2D1 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 적합합니다. 인간 및 마우스 시료에 반응하며, 막단백질 연구 및 알츠하이머 관련 연구에 유용합니다. 고순도 IgG 형태로 -20°C에서 1년간 보관 가능합니다.
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TM2D1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | TM2D1 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 22 kD |
| Gene ID (Human) | 83941 |
| Human Swiss-Prot No | Q9BX74 |
| Cellular localization | Membrane; Multi-pass membrane protein |
| Species Reactivity | Human; Mouse |
Background
The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and is known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established as a causative factor in neuron death and cognitive decline observed in Alzheimer’s disease. This protein may be a target of neurotoxic beta-amyloid peptide and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. Several transcript variants have been identified for this gene (RefSeq, Feb 2016).
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