Thermo Fisher Scientific Phospho-RCAN1 (Ser163) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human RCAN1(Accession P53805), corresponding to amino acid residues around phosphorylated Ser163. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RCAN1,uniProtId:P53805-1,ncbiNodeId:9606,antigenRange:163,antigenLength:252,antigenImageFileName:PA5-105993_RCAN1_P53805-1_Rabbit.svg,antigenImageFileNamePDP:PA5-105993_RCAN1_P53805-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2817392

Product Specific Information

Antibody detects endogenous levels of Calcipressin 1 only when phosphorylated at Ser163.

Target Information

The RCAN1 protein interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.