Thermo Fisher Scientific Phospho-EEF2K (Ser359) Polyclonal Antibody
EEF2K 단백질의 Ser359 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal Antibody. 인간, 마우스, 랫트 반응성. Western blot 및 Immunocytochemistry에 적합. 고순도 액상 형태로 연구용 단백질 인산화 분석에 활용 가능.
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Thermo Fisher Scientific Phospho-EEF2K (Ser359) Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:1,000–1:3,000
- Immunocytochemistry (ICC/IF): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EEF2K (Accession O00418), corresponding to amino acid residues around phosphorylated Ser359 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817393 |
Product Specific Information
Antibody detects endogenous levels of eEF2K only when phosphorylated at Ser359.
Target Information
EEF2K is a highly conserved serine/threonine kinase in the calmodulin signaling pathway whose activity is increased in cancers, including breast cancer.
EEF2K (eukaryotic elongation factor 2 kinase) regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by upstream kinases such as AMPK or TRPM7, EEF2K phosphorylates elongation factor EEF2 at a single site, rendering EEF2 unable to bind ribosomes and thereby reducing the rate of protein synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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