Thermo Fisher Scientific NKCC2 (extracellular) Polyclonal Antibody
Rabbit polyclonal antibody targeting extracellular NKCC2, validated for Western blot. Supplied lyophilized, reconstitutable in deionized water. Ideal for kidney-specific sodium-potassium-chloride cotransporter research. For research use only.
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1:400
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)GYKKNWRKAPLSELE, corresponding to amino acid residues 776–790 of rat NKCC2 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2736228 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitute using 50 µL deionized water.
Target Information
The sodium-potassium-chloride cotransporter isoform 2 (NKCC2) is kidney-specific and located on the apical membrane of the thick ascending limb of Henle's loop and the macula densa.
It mediates NaCl resorption with a stoichiometry of 1Na:1K:2Cl and is sensitive to diuretics such as furosemide and bumetanide.
Defects in this gene can lead to Bartter-like syndromes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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