Thermo Fisher Scientific NKCC2 (extracellular) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:400

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide (C)GYKKNWRKAPLSELE, corresponding to amino acid residues 776-790 of rat NKCC2 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NKCC2,uniProtId:P55016-1,ncbiNodeId:10114,antigenRange:776-790,antigenLength:1095,antigenImageFileName:PA5-77549_NKCC2_P55016-1_Rabbit.svg,antigenImageFileNamePDP:PA5-77549_NKCC2_P55016-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.8 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2736228

Product Specific Information

Product is shipped at room temperature as a lyophilized powder and should be stored at -20C upon receipt.

Reconstitute using 50 uL deionized water.

Target Information

The sodium-potassium-chloride cotransporter isoform 2 is kidney-specific and is found on the apical membrane of the thick ascending limb of Henle`s loop and the macula densa. It accounts for most of the NaCl resorption with the stoichiometry of 1Na:1K:2Cl and is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.