Thermo Fisher Scientific SLC28A2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide (C)EVTQGHSLKDGLGH, corresponding to amino acid residues 40-53 of rat Concentrative Nucleoside Transporter 2 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SLC28A2,uniProtId:Q62773-1,ncbiNodeId:10114,antigenRange:40-53,antigenLength:659,antigenImageFileName:PA5-77547_SLC28A2_Q62773-1_Rabbit.svg,antigenImageFileNamePDP:PA5-77547_SLC28A2_Q62773-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.8 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2736608

Product Specific Information

Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.

Target Information

The concentrative nucleoside transporter (CNT) family comprises three members: CNT1, CNT2 and CNT3. CNT2 participates in the absorption and disposition of endogenous nucleosides and mediates the first step of nucleotide biosynthesis. CNT2 levels are highly dependent on insulin (but not glucose) concentration, and the protein is under the control of the Adenosine 1 receptor. CNT family members are imperative in the response of cells to a variety of anticancer and antiviral nucleoside analogs, as the CNT proteins modulate their entry into target tissues. Increasing evidence also suggests that CNT2 may have a role in energy metabolism because activation of CNT2 relies on the opening of ATP-sensitive K+ channels.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.