Thermo Fisher Scientific LINGO1 (extracellular) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:2500

-

Immunohistochemistry (Frozen) (IHC (F))

1:400

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide (C)HVRSYSPDWPHQPNK, corresponding to amino acid residues 507- 521 of mouse LINGO-1 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LINGO1,uniProtId:Q9D1T0-1,ncbiNodeId:10090,antigenRange:507-521,antigenLength:614,antigenImageFileName:PA5-77544_LINGO1_Q9D1T0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-77544_LINGO1_Q9D1T0-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.8 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2736090

Product Specific Information

Product is shipped at room temperature as a lyophilized powder and should be stored at -20C upon receipt.

Reconstitute using 50 uL deionized water.

Target Information

Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.