
Thermo Fisher Scientific PLG Monoclonal Antibody (OTI4F5), TrueMAB
인간 PLG 단백질(Plasminogen)을 인식하는 OTI4F5 클론의 마우스 단일클론 항체입니다. IHC(P)에서 1:500 희석으로 검증되었습니다. 비결합형 액상 항체로, PBS/BSA/glycerol 완충액에 보관되며 -20°C에서 안정적으로 저장 가능합니다. 연구용으로만 사용됩니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested at 1:500 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4F5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 301–586 of human PLG produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Plasminogen is a plasma protein synthesized mainly in the liver. It consists of a single polypeptide chain with a molecular weight of 88.5 kDa and a plasma concentration typically between 70–200 mg/L. Activation by tissue-plasminogen activator, urokinase, or streptokinase converts plasminogen to plasmin through cleavage of the preactivation peptide. Plasmin comprises a heavy (A) chain with five kringles and a light (B) chain containing the active site. It is a trypsin-like protease that acts on fibrin, essential for fibrinolysis. Defects in plasmin activity can result in recurrent thrombosis, thrombophlebitis, and pulmonary embolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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