Thermo Fisher Scientific BAG5 Monoclonal Antibody (OTI2H6), TrueMAB
BAG5 단백질을 인식하는 Mouse monoclonal antibody로, Western blot에 최적화됨. Human BAG5 단백질과 반응하며, 1 mg/mL 농도의 액상 형태로 제공. Affinity chromatography로 정제되었으며, PBS, 1% BSA, 50% glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H6 |
| Immunogen | Full length human recombinant protein of human BAG5 produced in 293T |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
It has been hypothesized that the BAG-5 protein induces the death of nigral neurons through its interaction with hsp70, leading to increased protein aggregation and cell death by disinhibition of hsp70’s anti-apoptotic function. BAG-5 is believed to play an important role in neuronal death mechanisms and may modulate the hsp70/hsp40 chaperone axis. It might also coordinate localization or modulation of other BAG-containing proteins via BAG-BAG heterodimerization.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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