Thermo Fisher Scientific DHX36 Polyclonal Antibody
DHX36 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 등에 사용 가능. Human, Mouse, Rat 시료에 반응하며 항원 친화 크로마토그래피로 정제됨. 액상 형태로 4°C 또는 -20°C에서 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human DHX36. The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2735719 |
Product Specific Information
- Positive Control: 293T, A431, HeLa, HepG2
- Predicted Reactivity: Mouse (82%), Rat (80%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure.
DHX36 (DEAH box protein 36), also known as MLE-like protein 1 and RNA helicase associated with AU-rich element ARE (RHAU), belongs to the DEAH family of RNA helicases and may function in sex development and spermatogenesis.
It is expressed in testis and is evolutionarily conserved with true orthologs in almost all animal species. DHX36 plays a role in degradation and deadenylation of mRNAs containing in their 3′-UTR the consensus ARE sequence element and is required for early embryogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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