Thermo Fisher Scientific Human LGP2 Synthetic Peptide
인간 LGP2의 아미노 말단 14개 아미노산 서열을 기반으로 한 합성 펩타이드입니다. 항체 PA5-20434의 차단 펩타이드로 사용 가능하며, 항바이러스 선천 면역 연구에 적합합니다. 정제된 액상 형태로 제공되며 PBS buffer에 보존됩니다.
- 카탈로그번호
- PEP0551
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human LGP2 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 14 amino acids near the amino terminus of human LGP2.
PEP-0551 can be used as a blocking peptide with polyclonal antibody PA5-20434.
Target Information
Anti-viral innate immune responses are triggered by pathogen-associated molecular patterns (such as the accumulation of intracellular nucleic acids resulting from virus infections) and represent the first line of defense against numerous infectious organisms.
The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids. Other proteins that play similar roles, such as RIG-1 and MDA5, are members of a CARD-helicase family and are expressed in the cytoplasm.
A third protein, LGP2, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain. It is thought to act as an element of negative-feedback regulation of intracellular antiviral signaling. At least four isoforms of LGP2 are known to exist.
Usage Notes
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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