Thermo Fisher Scientific Human LGP2 Synthetic Peptide
인간 LGP2 단백질의 C-말단 12 아미노산 서열 기반 합성 펩타이드로, 항체 차단 실험용으로 적합합니다. 정제된 액상 형태이며 PBS 버퍼에 0.1% BSA와 0.02% sodium azide를 포함합니다. -20°C에서 보관하며 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PEP0550
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Product Specific Information
This peptide corresponds to 12 amino acids near the carboxy terminus of human LGP2.
PEP-0550 can be used as a blocking peptide with polyclonal antibody PA5-20433.
Target Information
Anti-viral innate immune responses are triggered by pathogen-associated molecular patterns, such as the accumulation of intracellular nucleic acids resulting from virus infections, and represent the first line of defense against numerous infectious organisms.
The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids.
Other proteins that play similar roles, such as RIG-1 and MDA5, are members of a CARD-helicase family and are expressed in the cytoplasm.
A third protein, LGP2, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain. It is thought to act as an element of negative-feedback regulation of intracellular antiviral signaling.
At least four isoforms of LGP2 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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