Thermo Fisher Scientific Phospho-BCAR1 (Tyr410) Polyclonal Antibody
Phospho-BCAR1 (Tyr410) 항체로 인간 및 생쥐 시료에서 p130Cas 단백질의 인산화 형태를 검출. Western blot 및 ELISA에 적합. 고순도 친화 크로마토그래피 정제. -20°C 보관, 동결·해동 반복 피할 것. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around Y410 of human BCAR1 (NP_0553822) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.94 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855520 |
Product Specific Information
Immunogen sequence: GVYAV
Target Information
The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signals via v-Crk and v-Src oncoproteins. It contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich region.
p130Cas is involved in biological processes such as cell adhesion, migration, growth factor stimulation, cytokine receptor engagement, and bacterial infection. Its physiological roles include cardiovascular development, actin filament assembly, and Src-induced cell transformation.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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