Thermo Fisher Scientific Phospho-BCAR1 (Tyr165) Polyclonal Antibody
Phospho-BCAR1 (Tyr165) 폴리클로날 항체로 인간, 마우스, 랫트 반응성. Western blot과 ELISA에 적합하며 고순도 친화 크로마토그래피 정제. 액상 형태로 안정적이며 -20°C에서 보관. 세포 신호전달 및 인산화 연구용.
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Thermo Fisher Scientific Phospho-BCAR1 (Tyr165) Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:2,000
- ELISA: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphorylated peptide around Tyr165 of human BCAR1 (NP_0553822) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.26 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855519 |
Product Specific Information
- Immunogen sequence: DLYQV
Target Information
The p130Cas (Crk-associated substrate) is a common cellular target of phosphorylation signals via v-Crk and v-Src oncoproteins.
It contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich region.
p130Cas is involved in various biological processes including:
- Cell adhesion and migration
- Growth factor stimulation
- Cytokine receptor engagement
- Bacterial infection
Physiological roles include cardiovascular development, actin filament assembly, and Src-induced cell transformation.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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