Thermo Fisher Scientific HMOX1 Monoclonal Antibody (GT664)
HMOX1 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot, ICC/IF, ELISA에 사용 가능. 인간에서 반응하며, 예측 반응종은 Mouse, Rat, Dog, Pig, Bovine. 단기 4°C 보관, 장기 -20°C 보관 권장. 연구용으로만 사용.
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Thermo Fisher Scientific HMOX1 Monoclonal Antibody (GT664)
Applications and Tested Dilutions
| Application | Tested Dilution | References |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
| ELISA | Assay-dependent | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT664 |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Heme Oxygenase 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787188 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (81%), Rat (80%), Dog (85%), Pig (82%), Bovine (83%)
- Positive Control: HeLa, HeLa 500 µM CoCl₂ treatment for 24 hr
- Centrifuge briefly prior to opening the vial.
Target Information
Heme oxygenase (HO) is a microsomal enzyme that catalyzes the oxidation of heme to biliverdin and carbon monoxide, both of which have antioxidant properties. HO consists of two homologous isozymes: an inducible HO-1 and a constitutively expressed HO-2.
HO-1 expression is induced by oxidative stress, inflammatory agents, transforming growth factor beta, and heat shock. Elevated HO-1 is considered a cellular defense mechanism against oxidative stress, as increased HO activity can generate more bilirubin, an antioxidant molecule.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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