Thermo Fisher Scientific Lamin A/C Polyclonal Antibody
Thermo Fisher Scientific의 Lamin A/C Polyclonal Antibody는 인간, 마우스, 랫트에 반응하는 rabbit IgG 형의 항체로, Western blot, IHC, ICC, ELISA, ChIP 등에 적합합니다. 고순도 친화 크로마토그래피 정제, 안정적인 PBS/glycerol 버퍼, -20°C 보관 조건으로 연구용에 최적화되어 있습니다.
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Thermo Fisher Scientific Lamin A/C Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| ChIP assay (ChIP) | 1:20–1:100 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 403–572 of human Lamin A/C (NP_7338211) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.26 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | −20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901127 |
Product Specific Information
- Positive Samples: HeLa, K-562, A-549
- Immunogen sequence:
SSHSSQTQGG GSVTKKRKLE STESRSSFSQ HARTSGRVAV EEVDEEGKFV RLRNKSNEDQ SMGNWQIKRQ NGDDPLLTYR FPPKFTLKAG QVVTIWAAGA GATHSPPTDL VWKAQNTWGC GNSLRTALIN STGEEVAMRK LVRSVTVVED DEDEDGDDLL HHHHGSHCSS
Target Information
Lamins are intermediate filament proteins forming a matrix on the inner surface of the nuclear envelope. Lamins A and C are alternatively spliced products of the LMNA gene. The LMNA gene is associated with various disorders including:
- Emery-Dreifuss muscular dystrophy
- Dunnigan-type familial partial lipodystrophy (FPLD)
- Limb-girdle muscular dystrophy (LGMD1B)
- Dilated cardiomyopathy (CMD1A)
- Axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1)
- Mandibuloacral dysplasia (MAD)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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