Thermo Fisher Scientific PD-L1 (CD274) Recombinant Rabbit Monoclonal Antibody (8E4V4)
PD-L1(CD274) 타겟을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단일클론 항체입니다. Western blot, IHC, ELISA 등에 적합하며, 인간 시료 반응성이 확인되었습니다. 고순도 액상 형태로 제공되며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Thermo Fisher Scientific PD-L1 (CD274) Recombinant Rabbit Monoclonal Antibody (8E4V4)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:400–1:1,600 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:500 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8E4V4 |
| Immunogen | Recombinant protein of human PD-L1 extracellular domain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | TBS, pH 7.3–7.7, with 1% BSA |
| Contains | <0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2897776 |
Product Specific Information
- Positive Samples: Raji
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a member of the B7 family. PD-L1 binds to its receptor PD-1, which negatively regulates T-cell receptor (TCR) signaling. This interaction decreases TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant in many murine and human cancers and can be up-regulated by IFN-gamma stimulation, suggesting its role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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