
Thermo Fisher Scientific GIRK1 Polyclonal Antibody, Biotin
GIRK1 단백질을 인식하는 Biotin 결합 폴리클로날 항체로, Western blot, IHC, ELISA, IP 등 다양한 응용 가능. Rabbit IgG 기반으로 높은 특이성과 감도를 제공. 인공 펩타이드 면역원 사용, 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 420–470 of rat GIRK1 protein (Kir3.1, KCNJ3, UniProt ID: P63251-1) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This potassium channel is controlled by G proteins. Inward rectifier potassium channels preferentially allow potassium to flow into the cell rather than out. Voltage dependence is influenced by extracellular potassium concentration, shifting channel opening to more positive voltages as external potassium increases. Inward rectification results mainly from blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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