Thermo Fisher Scientific GIRK1 Polyclonal Antibody
GIRK1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Human, Mouse, Rat 반응성. WB, IHC, ELISA, IP에 사용 가능. 합성 펩타이드(aa 420-470 rat GIRK1) 면역원. 연구용으로만 사용.
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Thermo Fisher Scientific GIRK1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 420–470 of rat GIRK1 protein (Kir3.1, KCNJ3, UniProt ID: P63251-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This potassium channel is controlled by G proteins. Inward rectifier potassium channels preferentially allow potassium to flow into the cell rather than out. Their voltage dependence is regulated by extracellular potassium concentration; as external potassium increases, the channel opening shifts to more positive voltages. Inward rectification is mainly due to blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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