Thermo Fisher Scientific ATP5A1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:200–1:2,000

Immunohistochemistry (IHC)

• Tested Dilution: 1:200–1:2,000

Product Specifications

Product Specific Information

• Reconstitute in 100 µL of sterile water.
• Centrifuge to remove any insoluble material.
• Specificity: ATP5A1.

Target Information

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation.
ATP synthase consists of two linked multi-subunit complexes:

• F1: the soluble catalytic core
• Fo: the membrane-spanning proton channel

The catalytic portion includes five subunits (α, β, γ, δ, ε) with a stoichiometry of 3α, 3β, and one each of the others.
The proton channel consists of three main subunits (a, b, c).
This gene encodes the α subunit of the catalytic core.
Alternatively spliced transcript variants encoding different isoforms have been identified.
Pseudogenes of this gene are located on chromosomes 9, 2, and 16.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.