Thermo Fisher Scientific AMPA 2 Polyclonal Antibody
AMPA 2 폴리클로날 항체로 인간, 마우스, 랫트 시료에 반응합니다. Western blot 및 IHC 실험에 적합하며, Glutamate receptor 2의 외부 도메인 펩타이드로부터 제작되었습니다. 동결건조 형태로 제공되며 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Thermo Fisher Scientific AMPA 2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | View references |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | View references |
| Miscellaneous PubMed (Misc) | – | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Goat / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from extracellular domain of human Glutamate receptor 2 (AMPA 2) conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and mouse.
- Specificity: AMPA 2.
Target Information
The ion channels activated by glutamate are divided into two classes:
- NMDA receptors (NMDAR), sensitive to N-methyl-D-aspartate.
- AMPA receptors (AMPAR), activated by alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid.
AMPARs consist of four distinct Glutamate Receptor Subunits (GluR1–4) and play key roles in excitatory neurotransmission in the brain. The GluR2 subunit is involved in synaptic plasticity, such as long-term depression (LTD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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