Thermo Fisher Scientific H3.3 K4M Recombinant Rabbit Monoclonal Antibody (16H24L10), ChIP-Verified
H3.3 K4M 변형 히스톤을 인식하는 재조합 토끼 단클론 항체로, ChIP 및 Western blot에 검증됨. Expi293 시스템에서 발현된 IgG 형식의 항체이며, Protein A로 정제됨. 인간 반응성이 확인되었으며, 마우스·랫·소에도 예측 반응.
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- 703833x (2개 옵션)
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| ChIP assay (ChIP) | 1–5 µg/million cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 16H24L10 |
| Immunogen | Peptide corresponding to human H3.3K4M [aa2–aa9] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2895883 |
Product Specific Information
This antibody is predicted to react with Mouse, Rat, and Bovine.
Target Information
Histone H3 is a DNA-binding protein found in the chromatin of all eukaryotic cells. Together with four core histone proteins, it binds to DNA forming the nucleosome structure. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Post-translational modifications of histones alter chromatin structure or enable specific transcription factor binding. The N-terminal tail of histone H3 can undergo modifications such as methylation, acetylation, and phosphorylation, influencing diverse cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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