Thermo Fisher Scientific NGAL Monoclonal Antibody (14)

Applications

Tested Dilution

Publications

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

14

Immunogen

Human recombinant NGAL coupled to carrier and adsorbed to aluminium hydroxide gel. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NGAL,uniProtId:P80188-1,ncbiNodeId:9606,antigenRange:1-198,antigenLength:198,antigenImageFileName:ABS_062-14-02_NGAL_P80188-1_House_mouse.svg,antigenImageFileNamePDP:ABS_062-14-02_NGAL_P80188-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.96 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4

Contains

15mM sodium azide

Storage conditions

4° C, store in dark

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2536233

Product Specific Information

Reactivity: ABS 062-14-02 binds human NGAL coated onto a solid phase. ABS 062-14-02 can be used as a detection antibody in a sandwich ELISA with capture antibodies HYB 211-01-02, ABS 038-04-02, ABS 038-14-02, ABS 038-15-02, ABS 038-23-02, ABS 038-26-02 and ABS 062-33-02. When ABS 062-14-02 is used as a biotinylated detection antibody with capture antibody ABS 062-33-02, the assay is specific for the NGAL monomer, cross-reacting less than 1% with NGAL homodimer.

NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL

Target Information

NGAL (Neutrophil gelatinase-associated lipocalin, lipocalin 2, siderocalin and neutrophil lipocalin) is a 25 kDa glycosylated single chain monomer and member of the lipocalin family of proteins that bind and transport small lipophilic molecules. NGAL is released by activated neutrophils, can form dimers and small amounts of higher oligomers, and complexes with matrix metalloproteinase 9 (MMP-9, gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by ischemic or nephrotoxic kidney injury.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.